STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDL2Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (302 aa)    
Predicted Functional Partners:
EPHB4
EPH receptor B4.
      
 0.566
STOML1
Stomatin like 1.
  
 0.553
PHB2
Prohibitin.
  
 0.553
NCSTN
Nicastrin.
      
 0.536
EFNB3
Ephrin B3; Belongs to the ephrin family.
    
 
 0.529
Parl
Rhomboid domain-containing protein.
      
 0.527
EFNB2
Ephrin B2; Belongs to the ephrin family.
    
 
 0.523
STOML3
Stomatin like 3.
  
 0.520
STOM
Stomatin.
  
 0.520
NPHS2
NPHS2 stomatin family member, podocin.
  
 0.520
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.