STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCATLecithin-cholesterol acyltransferase. (441 aa)    
Predicted Functional Partners:
APOA1
Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.
   
 0.989
APOA4
Apolipoprotein A4.
   
 0.963
APOC1
Apolipoprotein C1.
   
 
 0.962
PLD2
Phospholipase.
     
 0.935
PLD1
Phospholipase.
     
 0.935
CHPT1
Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.919
CEPT1
Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.919
PLAAT2
Phospholipase A and acyltransferase 2.
     
 0.918
PLAAT3
Phospholipase A and acyltransferase 3.
     
 0.918
PLD4
Phospholipase D family member 4.
   
 
 0.916
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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