STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IVDIsovaleryl-CoA dehydrogenase. (426 aa)    
Predicted Functional Partners:
MCCC2
Methylcrotonoyl-CoA carboxylase 2.
 
 
 0.967
ECI2
Enoyl-CoA delta isomerase 2.
  
 0.966
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.945
ETFA
Electron transfer flavoprotein subunit alpha.
 
 0.943
ENSCPOP00000022046
Thiolase_N domain-containing protein.
  
 0.942
ENSCPOP00000024929
SCP2 domain-containing protein.
  
 0.942
ETFB
Electron transfer flavoprotein subunit beta.
  
 0.939
Acaa1
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.928
Bckdha
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 
 0.920
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
  
 0.919
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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