STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APCSSerum amyloid P-component. (223 aa)    
Predicted Functional Partners:
FCGR2
Low affinity immunoglobulin gamma Fc region receptor II; Binds to the Fc region of immunoglobulins gamma. Low affinity receptor.
    
 
 0.814
CRP
C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity).
  
 
0.801
HRG
Histidine rich glycoprotein.
   
  
 0.761
LOC100727376
C-type lectin domain-containing protein.
   
 
 0.755
AFM
Afamin.
   
  
 0.730
Fcgr2a
Ig-like domain-containing protein.
    
 
 0.707
TTR
Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
   
 
 0.652
Masp2
CUB domain-containing protein.
   
 
 0.646
APOH
Apolipoprotein H.
   
 
 0.633
C4BPB
Complement component 4 binding protein beta.
   
 
 0.608
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.