STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS1Suppressor of cytokine signaling 1. (217 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.997
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.987
TYK2
Tyrosine-protein kinase.
   
 0.984
STAT1
Signal transducer and activator of transcription.
   
 0.973
STAT3
Signal transducer and activator of transcription.
   
 0.969
JAK1
Tyrosine-protein kinase.
   
 0.966
JAK3
Tyrosine-protein kinase.
   
 0.957
IRS1
Insulin receptor substrate 1.
    
 0.952
SOCS3
Suppressor of cytokine signaling 3.
   
 
0.948
Elob
Ubiquitin-like domain-containing protein.
    
 0.947
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.