Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GRIN2A | GRIN2B | ENSCPOP00000012192 | ENSCPOP00000005487 | Glutamate ionotropic receptor NMDA type subunit 2A. | Glutamate ionotropic receptor NMDA type subunit 2B. | 0.998 |
| GRIN2A | GRIN3A | ENSCPOP00000012192 | ENSCPOP00000006007 | Glutamate ionotropic receptor NMDA type subunit 2A. | Glutamate ionotropic receptor NMDA type subunit 3A. | 0.972 |
| GRIN2A | PDYN | ENSCPOP00000012192 | ENSCPOP00000019436 | Glutamate ionotropic receptor NMDA type subunit 2A. | Alpha-neoendorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity). Leumorphin has a typical opiod activity and may have anti- apoptotic effect. | 0.913 |
| GRIN2B | GRIN2A | ENSCPOP00000005487 | ENSCPOP00000012192 | Glutamate ionotropic receptor NMDA type subunit 2B. | Glutamate ionotropic receptor NMDA type subunit 2A. | 0.998 |
| GRIN2B | GRIN3A | ENSCPOP00000005487 | ENSCPOP00000006007 | Glutamate ionotropic receptor NMDA type subunit 2B. | Glutamate ionotropic receptor NMDA type subunit 3A. | 0.972 |
| GRIN2B | PDYN | ENSCPOP00000005487 | ENSCPOP00000019436 | Glutamate ionotropic receptor NMDA type subunit 2B. | Alpha-neoendorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity). Leumorphin has a typical opiod activity and may have anti- apoptotic effect. | 0.925 |
| GRIN3A | GRIN2A | ENSCPOP00000006007 | ENSCPOP00000012192 | Glutamate ionotropic receptor NMDA type subunit 3A. | Glutamate ionotropic receptor NMDA type subunit 2A. | 0.972 |
| GRIN3A | GRIN2B | ENSCPOP00000006007 | ENSCPOP00000005487 | Glutamate ionotropic receptor NMDA type subunit 3A. | Glutamate ionotropic receptor NMDA type subunit 2B. | 0.972 |
| GRIN3A | PDYN | ENSCPOP00000006007 | ENSCPOP00000019436 | Glutamate ionotropic receptor NMDA type subunit 3A. | Alpha-neoendorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity). Leumorphin has a typical opiod activity and may have anti- apoptotic effect. | 0.882 |
| OPRD1 | OPRK1 | ENSCPOP00000028801 | ENSCPOP00000005950 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. | Kappa-type opioid receptor; G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by r [...] | 0.810 |
| OPRD1 | OPRL1 | ENSCPOP00000028801 | ENSCPOP00000024516 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. | Nociceptin receptor; G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociceptio [...] | 0.735 |
| OPRD1 | OPRM1 | ENSCPOP00000028801 | ENSCPOP00000015591 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP- bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell ty [...] | 0.858 |
| OPRD1 | PDYN | ENSCPOP00000028801 | ENSCPOP00000019436 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. | Alpha-neoendorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity). Leumorphin has a typical opiod activity and may have anti- apoptotic effect. | 0.946 |
| OPRD1 | PENK | ENSCPOP00000028801 | ENSCPOP00000027030 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. | Met-enkephalin-Arg-Gly-Leu; Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(238-259) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum. | 0.991 |
| OPRD1 | PNOC | ENSCPOP00000028801 | ENSCPOP00000026399 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. | Prepronociceptin. | 0.885 |
| OPRD1 | POMC | ENSCPOP00000028801 | ENSCPOP00000020054 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. | Corticotropin-like intermediary peptide; ACTH stimulates the adrenal glands to release cortisol. Beta-endorphin and Met-enkephalin are endogenous opiates. [Melanocyte-stimulating hormone alpha]: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes. [Beta-endorphin]: Endogenous orexigenic opiate. | 0.947 |
| OPRK1 | OPRD1 | ENSCPOP00000005950 | ENSCPOP00000028801 | Kappa-type opioid receptor; G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by r [...] | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. | 0.810 |
| OPRK1 | OPRL1 | ENSCPOP00000005950 | ENSCPOP00000024516 | Kappa-type opioid receptor; G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by r [...] | Nociceptin receptor; G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociceptio [...] | 0.801 |
| OPRK1 | OPRM1 | ENSCPOP00000005950 | ENSCPOP00000015591 | Kappa-type opioid receptor; G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by r [...] | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP- bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell ty [...] | 0.833 |
| OPRK1 | PDYN | ENSCPOP00000005950 | ENSCPOP00000019436 | Kappa-type opioid receptor; G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by r [...] | Alpha-neoendorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity). Leumorphin has a typical opiod activity and may have anti- apoptotic effect. | 0.953 |
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