Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PALM2AKAP2 | PTTG1IP | ENSCPOP00000017270 | ENSCPOP00000019508 | PALM2-AKAP2 fusion. | PTTG1 interacting protein. | 0.437 |
| PTTG1IP | PALM2AKAP2 | ENSCPOP00000019508 | ENSCPOP00000017270 | PTTG1 interacting protein. | PALM2-AKAP2 fusion. | 0.437 |
| PTTG1IP | Pttg1 | ENSCPOP00000019508 | ENSCPOP00000031186 | PTTG1 interacting protein. | Uncharacterized protein. | 0.519 |
| PTTG1IP | SCPEP1 | ENSCPOP00000019508 | ENSCPOP00000002609 | PTTG1 interacting protein. | Carboxypeptidase; Belongs to the peptidase S10 family. | 0.552 |
| PTTG1IP | STX7 | ENSCPOP00000019508 | ENSCPOP00000027591 | PTTG1 interacting protein. | Syntaxin 7; Belongs to the syntaxin family. | 0.403 |
| PTTG1IP | SUOX | ENSCPOP00000019508 | ENSCPOP00000008936 | PTTG1 interacting protein. | Sulfite oxidase. | 0.554 |
| PTTG1IP | TP53 | ENSCPOP00000019508 | ENSCPOP00000029751 | PTTG1 interacting protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.633 |
| PTTG1IP | TP63 | ENSCPOP00000019508 | ENSCPOP00000027113 | PTTG1 interacting protein. | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | 0.582 |
| PTTG1IP | TP73 | ENSCPOP00000019508 | ENSCPOP00000028340 | PTTG1 interacting protein. | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. | 0.582 |
| Pttg1 | PTTG1IP | ENSCPOP00000031186 | ENSCPOP00000019508 | Uncharacterized protein. | PTTG1 interacting protein. | 0.519 |
| Pttg1 | TP53 | ENSCPOP00000031186 | ENSCPOP00000029751 | Uncharacterized protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.493 |
| SCPEP1 | PTTG1IP | ENSCPOP00000002609 | ENSCPOP00000019508 | Carboxypeptidase; Belongs to the peptidase S10 family. | PTTG1 interacting protein. | 0.552 |
| STX7 | PTTG1IP | ENSCPOP00000027591 | ENSCPOP00000019508 | Syntaxin 7; Belongs to the syntaxin family. | PTTG1 interacting protein. | 0.403 |
| SUOX | PTTG1IP | ENSCPOP00000008936 | ENSCPOP00000019508 | Sulfite oxidase. | PTTG1 interacting protein. | 0.554 |
| TP53 | PTTG1IP | ENSCPOP00000029751 | ENSCPOP00000019508 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | PTTG1 interacting protein. | 0.633 |
| TP53 | Pttg1 | ENSCPOP00000029751 | ENSCPOP00000031186 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Uncharacterized protein. | 0.493 |
| TP53 | TP63 | ENSCPOP00000029751 | ENSCPOP00000027113 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | 0.935 |
| TP53 | TP73 | ENSCPOP00000029751 | ENSCPOP00000028340 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. | 0.975 |
| TP63 | PTTG1IP | ENSCPOP00000027113 | ENSCPOP00000019508 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | PTTG1 interacting protein. | 0.582 |
| TP63 | TP53 | ENSCPOP00000027113 | ENSCPOP00000029751 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.935 |
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