STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H0W987_CAVPOUncharacterized protein; Belongs to the cytochrome P450 family. (386 aa)    
Predicted Functional Partners:
CYP1A1
Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]
  
 0.918
CYP2E1
Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.
  
 0.918
LOC100720199
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 0.915
CYP2S1
Cytochrome P450 family 2 subfamily S member 1.
  
 0.914
LOC100716044
Cytochrome P450 2C-like protein; Belongs to the cytochrome P450 family.
  
 0.914
CYP26C1
Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family.
  
 
 0.898
CYP26B1
Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.
  
 0.898
CYP26A1
Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 0.893
CYP7A1
Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 
 0.883
LOC100713503
Uncharacterized protein; Belongs to the cytochrome P450 family.
 
0.867
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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