node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYP1A1 | CYP26A1 | ENSCPOP00000014064 | ENSCPOP00000014544 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.933 |
CYP1A1 | CYP26B1 | ENSCPOP00000014064 | ENSCPOP00000005814 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.935 |
CYP1A1 | CYP26C1 | ENSCPOP00000014064 | ENSCPOP00000003439 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. | 0.928 |
CYP1A1 | CYP2E1 | ENSCPOP00000014064 | ENSCPOP00000024284 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.931 |
CYP1A1 | CYP2S1 | ENSCPOP00000014064 | ENSCPOP00000006732 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | Cytochrome P450 family 2 subfamily S member 1. | 0.921 |
CYP1A1 | CYP7A1 | ENSCPOP00000014064 | ENSCPOP00000003062 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.955 |
CYP1A1 | H0W987_CAVPO | ENSCPOP00000014064 | ENSCPOP00000019545 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.918 |
CYP1A1 | LOC100713503 | ENSCPOP00000014064 | ENSCPOP00000019481 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.931 |
CYP1A1 | LOC100716044 | ENSCPOP00000014064 | ENSCPOP00000008690 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | Cytochrome P450 2C-like protein; Belongs to the cytochrome P450 family. | 0.924 |
CYP1A1 | LOC100720199 | ENSCPOP00000014064 | ENSCPOP00000010070 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.924 |
CYP26A1 | CYP1A1 | ENSCPOP00000014544 | ENSCPOP00000014064 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] | 0.933 |
CYP26A1 | CYP26B1 | ENSCPOP00000014544 | ENSCPOP00000005814 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.920 |
CYP26A1 | CYP26C1 | ENSCPOP00000014544 | ENSCPOP00000003439 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. | 0.922 |
CYP26A1 | CYP2E1 | ENSCPOP00000014544 | ENSCPOP00000024284 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.562 |
CYP26A1 | CYP2S1 | ENSCPOP00000014544 | ENSCPOP00000006732 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily S member 1. | 0.934 |
CYP26A1 | CYP7A1 | ENSCPOP00000014544 | ENSCPOP00000003062 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.656 |
CYP26A1 | H0W987_CAVPO | ENSCPOP00000014544 | ENSCPOP00000019545 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.893 |
CYP26A1 | LOC100713503 | ENSCPOP00000014544 | ENSCPOP00000019481 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.929 |
CYP26A1 | LOC100716044 | ENSCPOP00000014544 | ENSCPOP00000008690 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 2C-like protein; Belongs to the cytochrome P450 family. | 0.930 |
CYP26A1 | LOC100720199 | ENSCPOP00000014544 | ENSCPOP00000010070 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.930 |