STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDSS1Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (414 aa)    
Predicted Functional Partners:
COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
  
 
 0.968
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 0.933
Fntb
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
   
 0.906
PSMD3
Proteasome 26S subunit, non-ATPase 3.
 
      0.900
PDSS2
Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family.
  
  
0.900
MVD
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
 0.892
GGPS1
Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.
     
 0.887
DHDDS
Alkyl transferase; Belongs to the UPP synthase family.
  
 
 0.876
IDI1
Isopentenyl-diphosphate delta isomerase 1.
  
 
 0.875
FDPS
Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
    
 0.874
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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