node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGT | BDKRB2 | ENSCPOP00000021272 | ENSCPOP00000020477 | Angiotensinogen; Belongs to the serpin family. | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | 0.960 |
AGT | GNA11 | ENSCPOP00000021272 | ENSCPOP00000021515 | Angiotensinogen; Belongs to the serpin family. | G protein subunit alpha 11. | 0.638 |
AGT | GNA14 | ENSCPOP00000021272 | ENSCPOP00000004849 | Angiotensinogen; Belongs to the serpin family. | G protein subunit alpha 14. | 0.592 |
AGT | GNAQ | ENSCPOP00000021272 | ENSCPOP00000026700 | Angiotensinogen; Belongs to the serpin family. | G protein subunit alpha q. | 0.638 |
AGT | KNG1 | ENSCPOP00000021272 | ENSCPOP00000011479 | Angiotensinogen; Belongs to the serpin family. | Kininogen 1. | 0.750 |
AGT | OPRD1 | ENSCPOP00000021272 | ENSCPOP00000028801 | Angiotensinogen; Belongs to the serpin family. | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. | 0.610 |
BDKRB2 | AGT | ENSCPOP00000020477 | ENSCPOP00000021272 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | Angiotensinogen; Belongs to the serpin family. | 0.960 |
BDKRB2 | GNA11 | ENSCPOP00000020477 | ENSCPOP00000021515 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | G protein subunit alpha 11. | 0.940 |
BDKRB2 | GNA14 | ENSCPOP00000020477 | ENSCPOP00000004849 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | G protein subunit alpha 14. | 0.938 |
BDKRB2 | GNAI2 | ENSCPOP00000020477 | ENSCPOP00000025341 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. | 0.930 |
BDKRB2 | GNAI3 | ENSCPOP00000020477 | ENSCPOP00000010346 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...] | 0.930 |
BDKRB2 | GNAQ | ENSCPOP00000020477 | ENSCPOP00000026700 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | G protein subunit alpha q. | 0.940 |
BDKRB2 | GNG12 | ENSCPOP00000020477 | ENSCPOP00000026218 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.929 |
BDKRB2 | Gna15 | ENSCPOP00000020477 | ENSCPOP00000004478 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | Uncharacterized protein. | 0.929 |
BDKRB2 | KNG1 | ENSCPOP00000020477 | ENSCPOP00000011479 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | Kininogen 1. | 0.999 |
BDKRB2 | OPRD1 | ENSCPOP00000020477 | ENSCPOP00000028801 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. | 0.913 |
GNA11 | AGT | ENSCPOP00000021515 | ENSCPOP00000021272 | G protein subunit alpha 11. | Angiotensinogen; Belongs to the serpin family. | 0.638 |
GNA11 | BDKRB2 | ENSCPOP00000021515 | ENSCPOP00000020477 | G protein subunit alpha 11. | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | 0.940 |
GNA11 | GNAI2 | ENSCPOP00000021515 | ENSCPOP00000025341 | G protein subunit alpha 11. | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. | 0.530 |
GNA11 | GNAI3 | ENSCPOP00000021515 | ENSCPOP00000010346 | G protein subunit alpha 11. | Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...] | 0.530 |