STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H0WDX0_CAVPOProtein kinase domain-containing protein. (809 aa)    
Predicted Functional Partners:
MAD1L1
Mitotic arrest deficient 1 like 1.
    
 0.974
NDC80
NDC80 kinetochore complex component.
   
 
 0.974
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 
 0.969
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.959
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 
 0.958
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.942
Bub1b
Uncharacterized protein.
   
 
 0.927
DLGAP5
DLG associated protein 5.
   
  
 0.900
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.894
NCAPG
Non-SMC condensin I complex subunit G.
   
  
 0.886
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.