STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT5Keratin 5; Belongs to the intermediate filament family. (583 aa)    
Predicted Functional Partners:
KRT14
Keratin 14; Belongs to the intermediate filament family.
  
0.998
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.845
RANBP2
RAN binding protein 2.
    
 0.727
KRT2
Keratin 2; Belongs to the intermediate filament family.
  
 
0.718
ACTR5
Actin related protein 5; Belongs to the actin family.
    
 0.696
TP63
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
   
 
 0.688
NFRKB
Nuclear factor related to kappaB binding protein.
    
 0.685
MCRS1
Microspherule protein 1.
    
 0.684
INO80
INO80 complex ATPase subunit.
    
  0.661
H0VI45_CAVPO
zf-C3Hc3H domain-containing protein.
    
 0.658
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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