STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100719669Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (299 aa)    
Predicted Functional Partners:
TUBA8
Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
    
  0.774
TUBA4A
Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
    
  0.774
Casp7
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.742
DFFA
DNA fragmentation factor subunit alpha.
    
 0.740
H0W5F0_CAVPO
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
    
 0.740
MET
MET proto-oncogene, receptor tyrosine kinase.
    
  0.738
MST1R
Macrophage stimulating 1 receptor.
    
  0.738
Casp3
CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.
    
 0.734
LMNA
Lamin A/C; Belongs to the intermediate filament family.
    
 0.727
LMNB1
Lamin B1; Belongs to the intermediate filament family.
    
 0.719
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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