STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLEC12AC-type lectin domain family 12 member A. (269 aa)    
Predicted Functional Partners:
CD69
CD69 molecule.
   
 0.908
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.782
LOC100723644
C-type lectin domain-containing protein.
   
 
0.754
LOC100722817
C-type lectin domain-containing protein.
   
 
0.754
LOC106026888
MHC_I-like_Ag-recog domain-containing protein.
    
 0.749
STX18
Syntaxin 18.
    
   0.655
COLEC11
Collectin subfamily member 11.
     
 0.642
FCER1G
High affinity immunoglobulin epsilon receptor subunit gamma; Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils priming T-cells toward effector T-helper 2 subset. Associates with pattern recognition receptors CLEC4D and CLEC4E to form a functi [...]
   
 0.602
Gosr2
Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
    
  0.594
TYROBP
TYRO protein tyrosine kinase binding protein.
   
 0.584
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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