PTPN1 protein (Cavia porcellus) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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[Homology]

Score

PTPN1

Tyrosine-protein phosphatase non-receptor type. (432 aa)

Predicted Functional Partners:

INSR

0.998

IGF1R

0.989

INSRR

0.966

IRS1

0.953

EGFR

0.952

PTPN11

0.945

CTNNB1

0.936

PTPRF

0.935

JAK2

0.931

JAK3

0.881

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	EGFR	ENSCPOP00000032871	ENSCPOP00000000034	Catenin beta 1.	Receptor protein-tyrosine kinase.	0.951
CTNNB1	IGF1R	ENSCPOP00000032871	ENSCPOP00000004859	Catenin beta 1.	Tyrosine-protein kinase receptor.	0.954
CTNNB1	INSR	ENSCPOP00000032871	ENSCPOP00000011692	Catenin beta 1.	Tyrosine-protein kinase receptor.	0.785
CTNNB1	INSRR	ENSCPOP00000032871	ENSCPOP00000002888	Catenin beta 1.	Insulin receptor-related protein alpha chain; Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB (By similarity).	0.775
CTNNB1	JAK2	ENSCPOP00000032871	ENSCPOP00000013203	Catenin beta 1.	Tyrosine-protein kinase.	0.497
CTNNB1	JAK3	ENSCPOP00000032871	ENSCPOP00000026323	Catenin beta 1.	Tyrosine-protein kinase.	0.432
CTNNB1	PTPN1	ENSCPOP00000032871	ENSCPOP00000022412	Catenin beta 1.	Tyrosine-protein phosphatase non-receptor type.	0.936
CTNNB1	PTPN11	ENSCPOP00000032871	ENSCPOP00000012179	Catenin beta 1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.577
CTNNB1	PTPRF	ENSCPOP00000032871	ENSCPOP00000009285	Catenin beta 1.	Protein tyrosine phosphatase receptor type F.	0.952
EGFR	CTNNB1	ENSCPOP00000000034	ENSCPOP00000032871	Receptor protein-tyrosine kinase.	Catenin beta 1.	0.951
EGFR	IGF1R	ENSCPOP00000000034	ENSCPOP00000004859	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.945
EGFR	INSR	ENSCPOP00000000034	ENSCPOP00000011692	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.852
EGFR	INSRR	ENSCPOP00000000034	ENSCPOP00000002888	Receptor protein-tyrosine kinase.	Insulin receptor-related protein alpha chain; Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB (By similarity).	0.774
EGFR	IRS1	ENSCPOP00000000034	ENSCPOP00000004880	Receptor protein-tyrosine kinase.	Insulin receptor substrate 1.	0.816
EGFR	JAK2	ENSCPOP00000000034	ENSCPOP00000013203	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.935
EGFR	JAK3	ENSCPOP00000000034	ENSCPOP00000026323	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.866
EGFR	PTPN1	ENSCPOP00000000034	ENSCPOP00000022412	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase non-receptor type.	0.952
EGFR	PTPN11	ENSCPOP00000000034	ENSCPOP00000012179	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.998
EGFR	PTPRF	ENSCPOP00000000034	ENSCPOP00000009285	Receptor protein-tyrosine kinase.	Protein tyrosine phosphatase receptor type F.	0.550
IGF1R	CTNNB1	ENSCPOP00000004859	ENSCPOP00000032871	Tyrosine-protein kinase receptor.	Catenin beta 1.	0.954