STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCPOP00000023065ANK_REP_REGION domain-containing protein. (179 aa)    
Predicted Functional Partners:
PSMD4
Proteasome 26S subunit, non-ATPase 4.
   
 0.932
PSMC5
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
   
 0.931
PSMC6
Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.
   
 0.929
PSMD11
Proteasome 26S subunit, non-ATPase 11.
   
 0.928
PSMD1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
    
 0.928
PSMC3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
   
 0.928
UCHL5
Ubiquitin carboxyl-terminal hydrolase.
    
 0.927
PSMD13
Proteasome 26S subunit, non-ATPase 13.
    
 0.927
PSMC1
Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family.
   
 0.926
PSMC4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
    
 0.925
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.