STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METTL22Methyltransferase like 22. (401 aa)    
Predicted Functional Partners:
KIN
Kin17 DNA and RNA binding protein.
    
 0.942
EEF2
Eukaryotic translation elongation factor 2.
    
 0.827
CC2D2A
Coiled-coil and C2 domain containing 2A.
    
 0.722
B9D1
B9 domain containing 1.
    
 0.717
B9D2
B9 domain containing 2.
    
 0.717
MKS1
MKS transition zone complex subunit 1.
    
 0.675
GFM1
Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...]
    
 0.651
EFL1
Elongation factor like GTPase 1.
    
 0.651
EFTUD2
Elongation factor Tu GTP binding domain containing 2.
    
 0.651
METTL21A
Methyltransferase like 21A.
   
 
 0.612
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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