node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AASDH | RUNX1T1 | ENSCPOP00000000189 | ENSCPOP00000023431 | Aminoadipate-semialdehyde dehydrogenase. | RUNX1 partner transcriptional co-repressor 1. | 0.805 |
Cebpa | RUNX1 | ENSCPOP00000015836 | ENSCPOP00000021315 | Uncharacterized protein. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.711 |
Cebpa | RUNX1T1 | ENSCPOP00000015836 | ENSCPOP00000023431 | Uncharacterized protein. | RUNX1 partner transcriptional co-repressor 1. | 0.827 |
Cebpa | SPI1 | ENSCPOP00000015836 | ENSCPOP00000015005 | Uncharacterized protein. | Spi-1 proto-oncogene. | 0.821 |
Med17 | RUNX1T1 | ENSCPOP00000012747 | ENSCPOP00000023431 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | RUNX1 partner transcriptional co-repressor 1. | 0.790 |
NCOR1 | NCOR2 | ENSCPOP00000000762 | ENSCPOP00000015192 | Nuclear receptor corepressor 1. | Nuclear receptor corepressor 2. | 0.926 |
NCOR1 | RUNX1T1 | ENSCPOP00000000762 | ENSCPOP00000023431 | Nuclear receptor corepressor 1. | RUNX1 partner transcriptional co-repressor 1. | 0.851 |
NCOR2 | NCOR1 | ENSCPOP00000015192 | ENSCPOP00000000762 | Nuclear receptor corepressor 2. | Nuclear receptor corepressor 1. | 0.926 |
NCOR2 | RUNX1T1 | ENSCPOP00000015192 | ENSCPOP00000023431 | Nuclear receptor corepressor 2. | RUNX1 partner transcriptional co-repressor 1. | 0.970 |
PRKAR2A | RUNX1T1 | ENSCPOP00000001101 | ENSCPOP00000023431 | Protein kinase cAMP-dependent type II regulatory subunit alpha. | RUNX1 partner transcriptional co-repressor 1. | 0.920 |
RUNX1 | Cebpa | ENSCPOP00000021315 | ENSCPOP00000015836 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Uncharacterized protein. | 0.711 |
RUNX1 | RUNX1T1 | ENSCPOP00000021315 | ENSCPOP00000023431 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | RUNX1 partner transcriptional co-repressor 1. | 0.851 |
RUNX1 | SPI1 | ENSCPOP00000021315 | ENSCPOP00000015005 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Spi-1 proto-oncogene. | 0.656 |
RUNX1 | TCF12 | ENSCPOP00000021315 | ENSCPOP00000008217 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Transcription factor 12. | 0.540 |
RUNX1 | TCF4 | ENSCPOP00000021315 | ENSCPOP00000004736 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Transcription factor 4. | 0.540 |
RUNX1T1 | AASDH | ENSCPOP00000023431 | ENSCPOP00000000189 | RUNX1 partner transcriptional co-repressor 1. | Aminoadipate-semialdehyde dehydrogenase. | 0.805 |
RUNX1T1 | Cebpa | ENSCPOP00000023431 | ENSCPOP00000015836 | RUNX1 partner transcriptional co-repressor 1. | Uncharacterized protein. | 0.827 |
RUNX1T1 | Med17 | ENSCPOP00000023431 | ENSCPOP00000012747 | RUNX1 partner transcriptional co-repressor 1. | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.790 |
RUNX1T1 | NCOR1 | ENSCPOP00000023431 | ENSCPOP00000000762 | RUNX1 partner transcriptional co-repressor 1. | Nuclear receptor corepressor 1. | 0.851 |
RUNX1T1 | NCOR2 | ENSCPOP00000023431 | ENSCPOP00000015192 | RUNX1 partner transcriptional co-repressor 1. | Nuclear receptor corepressor 2. | 0.970 |