STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT77Keratin 77; Belongs to the intermediate filament family. (575 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.845
RANBP2
RAN binding protein 2.
    
 0.727
ACTR5
Actin related protein 5; Belongs to the actin family.
    
 0.696
NFRKB
Nuclear factor related to kappaB binding protein.
    
 0.685
MCRS1
Microspherule protein 1.
    
 0.684
KRT2
Keratin 2; Belongs to the intermediate filament family.
  
 
0.667
INO80
INO80 complex ATPase subunit.
    
  0.661
H0VI45_CAVPO
zf-C3Hc3H domain-containing protein.
    
 0.658
TFPT
TCF3 fusion partner.
    
 0.657
INO80C
INO80 complex subunit C.
    
 0.656
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.