STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUDT2Nudix hydrolase 2. (147 aa)    
Predicted Functional Partners:
CTPS1
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 
 0.931
CTPS2
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 
 0.931
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
    
 0.920
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
    
 0.917
NME2
Nucleoside diphosphate kinase.
  
 
 0.917
NME4
Nucleoside diphosphate kinase.
  
 
 0.915
ADCY9
Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.914
NPR2
Guanylate cyclase.
    
 0.913
GUCY2C
Heat-stable enterotoxin receptor; Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.913
NPR1
Guanylate cyclase.
    
 0.913
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.