IMPACT protein (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Experiments

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[Homology]

Score

IMPACT

Impact RWD domain protein. (318 aa)

Predicted Functional Partners:

GRHPR

0.895

CMPK2

0.880

DTYMK

0.880

Gcsh

0.876

TK1

0.875

GLDC

0.862

Dhfr

0.862

PHGDH

0.822

CTBP1

0.822

CTBP2

0.822

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMPK2	DTYMK	ENSCPOP00000001000	ENSCPOP00000016293	Cytidine/uridine monophosphate kinase 2.	Deoxythymidylate kinase.	0.553
CMPK2	Dhfr	ENSCPOP00000001000	ENSCPOP00000028779	Cytidine/uridine monophosphate kinase 2.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.935
CMPK2	IMPACT	ENSCPOP00000001000	ENSCPOP00000024115	Cytidine/uridine monophosphate kinase 2.	Impact RWD domain protein.	0.880
CMPK2	TK1	ENSCPOP00000001000	ENSCPOP00000029380	Cytidine/uridine monophosphate kinase 2.	Thymidine kinase.	0.945
CTBP1	CTBP2	ENSCPOP00000017468	ENSCPOP00000032434	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 2.	0.989
CTBP1	Dhfr	ENSCPOP00000017468	ENSCPOP00000028779	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.595
CTBP1	GLDC	ENSCPOP00000017468	ENSCPOP00000004360	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.864
CTBP1	GRHPR	ENSCPOP00000017468	ENSCPOP00000011402	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.785
CTBP1	Gcsh	ENSCPOP00000017468	ENSCPOP00000008959	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.848
CTBP1	IMPACT	ENSCPOP00000017468	ENSCPOP00000024115	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Impact RWD domain protein.	0.822
CTBP1	PHGDH	ENSCPOP00000017468	ENSCPOP00000006066	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.626
CTBP2	CTBP1	ENSCPOP00000032434	ENSCPOP00000017468	C-terminal binding protein 2.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.989
CTBP2	Dhfr	ENSCPOP00000032434	ENSCPOP00000028779	C-terminal binding protein 2.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.595
CTBP2	GLDC	ENSCPOP00000032434	ENSCPOP00000004360	C-terminal binding protein 2.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.864
CTBP2	GRHPR	ENSCPOP00000032434	ENSCPOP00000011402	C-terminal binding protein 2.	Glyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.775
CTBP2	Gcsh	ENSCPOP00000032434	ENSCPOP00000008959	C-terminal binding protein 2.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.848
CTBP2	IMPACT	ENSCPOP00000032434	ENSCPOP00000024115	C-terminal binding protein 2.	Impact RWD domain protein.	0.822
CTBP2	PHGDH	ENSCPOP00000032434	ENSCPOP00000006066	C-terminal binding protein 2.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.592
DTYMK	CMPK2	ENSCPOP00000016293	ENSCPOP00000001000	Deoxythymidylate kinase.	Cytidine/uridine monophosphate kinase 2.	0.553
DTYMK	Dhfr	ENSCPOP00000016293	ENSCPOP00000028779	Deoxythymidylate kinase.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.935