STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGFBPL1Insulin like growth factor binding protein like 1. (275 aa)    
Predicted Functional Partners:
FBXO47
F-box protein 47.
   
    0.588
FREM1
FRAS1 related extracellular matrix 1.
      
 0.557
FREM3
FRAS1 related extracellular matrix 3.
      
 0.557
JUN
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
    
  0.524
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
      
 0.504
MIPOL1
Mirror-image polydactyly 1.
      
 0.459
FAM20B
FAM20B glycosaminoglycan xylosylkinase.
   
 
  0.459
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
   
 
  0.451
IGF2
Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is r [...]
    
 
 0.451
LIX1L
Limb and CNS expressed 1 like.
   
    0.445
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.