STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK4Polo like kinase 4. (958 aa)    
Predicted Functional Partners:
CEP192
Centrosomal protein 192.
    
 0.996
CEP152
Centrosomal protein 152.
   
 0.995
STIL
STIL centriolar assembly protein.
   
 0.994
RANBP2
RAN binding protein 2.
   
 0.978
ITSN2
Intersectin 2.
    
 0.975
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.962
ESPL1
Extra spindle pole bodies like 1, separase.
   
 0.959
CEP135
Centrosomal protein 135.
   
 0.950
PLK3
Serine/threonine-protein kinase PLK.
   
0.945
PLK2
Serine/threonine-protein kinase PLK.
   
0.945
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.