STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PUS3Pseudouridine synthase 3. (480 aa)    
Predicted Functional Partners:
MRPL17
Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
  
  
 0.865
TRUB2
TruB pseudouridine synthase family member 2.
  
 0.856
Trub1
TruB_N domain-containing protein.
  
 0.838
ENSCPOP00000027781
TruB_N domain-containing protein.
  
 0.838
POLR2C
RNA polymerase II subunit C.
  
  
 0.836
POLR1C
RNA polymerase I and III subunit C.
  
  
 0.836
WDR4
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.
   
 
 0.833
PUS7
Pseudouridine synthase 7.
  
 
 0.818
DKC1
Dyskerin pseudouridine synthase 1.
  
 0.813
NOC2L
NOC2 like nucleolar associated transcriptional repressor.
   
    0.782
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.