STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNASE1L3Deoxyribonuclease; Belongs to the DNase I family. (302 aa)    
Predicted Functional Partners:
SIN3A
SIN3 transcription regulator family member A.
    
 0.739
SIN3B
SIN3 transcription regulator family member B.
    
 0.739
LAMTOR2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
    
 0.648
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.641
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.641
TBK1
TANK binding kinase 1.
    
 0.641
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.641
OPTN
Optineurin.
   
 0.628
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
   
 0.628
LAMTOR1
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.
    
 0.616
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.