STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLX3T cell leukemia homeobox 3. (300 aa)    
Predicted Functional Partners:
LMX1B
LIM homeobox transcription factor 1 beta.
    
 
 0.698
ARX
Aristaless related homeobox.
    
 
 0.663
PAX2
Paired box 2.
      
 0.636
LHX1
LIM homeobox 1.
    
 
 0.571
LHX5
LIM homeobox 5.
    
 
 0.564
ISL1
ISL LIM homeobox 1.
   
 
 0.531
PTF1A
Pancreas associated transcription factor 1a.
      
 0.500
OLIG3
Oligodendrocyte transcription factor 3.
      
 0.479
NTS
Neurotensin.
      
 0.474
GAD2
Glutamate decarboxylase 2.
      
 0.472
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.