STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY3Sprouty RTK signaling antagonist 3. (288 aa)    
Predicted Functional Partners:
CBLB
Cbl proto-oncogene B.
    
 0.849
CBLC
Cbl proto-oncogene C.
    
 0.849
CBL
Cbl proto-oncogene.
    
 0.849
GRAP
GRB2 related adaptor protein.
    
 0.687
GRAP2
GRB2 related adaptor protein 2.
    
 0.687
GRB2
Growth factor receptor bound protein 2.
    
 0.687
SPRY1
Sprouty RTK signaling antagonist 1.
   
0.670
PPP2CB
Serine/threonine-protein phosphatase.
    
 0.642
PPP2CA
Serine/threonine-protein phosphatase.
    
 0.642
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
  0.613
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.