STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXO4Forkhead box O4. (505 aa)    
Predicted Functional Partners:
AKT3
AKT serine/threonine kinase 3.
    
 0.971
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.971
SIRT1
Sirtuin 1.
    
 0.946
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.946
SGK2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.942
PRMT1
Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
    
 0.937
STK11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
 0.936
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.935
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.935
MAPK8
Mitogen-activated protein kinase.
    
 0.933
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.