STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DKKL1Dickkopf like acrosomal protein 1. (231 aa)    
Predicted Functional Partners:
TNK2
Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
    0.724
TNFRSF13C
TNF receptor superfamily member 13C.
    
 0.633
C8B
Complement C8 beta chain.
   
 0.629
TNFRSF17
TNF receptor superfamily member 17.
    
 0.606
IL33
Interleukin 33.
    
 0.599
C7
Complement C7.
   
  0.598
TNK1
Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
    0.590
CCDC155
Coiled-coil domain containing 155.
     
 0.577
TNFRSF13B
TNF receptor superfamily member 13B.
    
 0.556
LRP5
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.545
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.