STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQSEC1IQ motif and Sec7 domain 1. (1112 aa)    
Predicted Functional Partners:
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.814
CYTH4
Cytohesin 4.
    
0.757
CYTH2
Uncharacterized protein.
    
0.732
ARFGEF1
ADP ribosylation factor guanine nucleotide exchange factor 1.
     
0.696
ARF1
ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.695
PSD2
Pleckstrin and Sec7 domain containing 2.
     
0.693
PSD3
Pleckstrin and Sec7 domain containing 3.
     
0.693
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
     
0.690
CYTH3
Cytohesin 3.
    
0.623
ARF5
ADP ribosylation factor 5; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.615
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.