STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (857 aa)    
Predicted Functional Partners:
GDPD1
Glycerophosphodiester phosphodiesterase domain containing 1.
  
 
 0.962
GDPD3
Glycerophosphodiester phosphodiesterase domain containing 3.
  
 
 0.961
ENPP6
Ectonucleotide pyrophosphatase/phosphodiesterase 6.
  
  
0.925
LPCAT4
Lysophosphatidylcholine acyltransferase 4.
   
 
  0.909
COASY
Coenzyme A synthase.
    
  0.875
PANK4
4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway.
     
 0.867
PLA2G4A
Phospholipase A2.
   
 
 0.862
PLA2G10
Phospholipase A(2).
     
 0.821
PLA2G1B
Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family.
     
 0.815
PLA2G6
Phospholipase A2 group VI.
    
 0.810
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.