STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)    
Predicted Functional Partners:
WAS
WASP actin nucleation promoting factor.
   
 0.927
WASL
WASP like actin nucleation promoting factor.
   
 0.915
H0UXA2_CAVPO
Uncharacterized protein.
 
    
 0.904
WIPF2
WAS/WASL interacting protein family member 2.
    
 
 0.897
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.761
CALM2
Calmodulin isoform 3; Belongs to the calmodulin family.
    
 
 0.681
CALM1
Calmodulin 1; Belongs to the calmodulin family.
    
 
 0.681
H0VKV0_CAVPO
Uncharacterized protein; Belongs to the calmodulin family.
    
 
 0.681
CALML3
Calmodulin like 3; Belongs to the calmodulin family.
    
 
 0.681
EFCAB3
EF-hand calcium binding domain 3.
    
 
 0.681
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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