STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNS1Tensin 1. (1593 aa)    
Predicted Functional Partners:
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.980
MST1R
Macrophage stimulating 1 receptor.
   
 0.980
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.911
INPPL1
Inositol polyphosphate phosphatase like 1.
   
 
 0.884
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
  
 0.847
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.842
PI4KA
Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.
     
 0.835
Itgb3
Integrin beta; Belongs to the integrin beta chain family.
    
 0.832
INPP5F
Inositol polyphosphate-5-phosphatase F.
   
 
  0.830
ITGB6
Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity).
    
 0.812
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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