STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2AC20Histone H2A; Belongs to the histone H2A family. (110 aa)    
Predicted Functional Partners:
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.991
KDM6B
Lysine demethylase 6B.
    
  0.811
KDM6A
Lysine demethylase 6A.
    
  0.811
H2AZ2
Histone H2A; Belongs to the histone H2A family.
  
0.759
H2AZ1
Histone H2A; Belongs to the histone H2A family.
  
0.759
LOC111756490
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.756
LOC100733876
annotation not available
 
 
 0.756
ENSCPOP00000024347
annotation not available
 
 
 0.756
LOC100728325
annotation not available
 
 
 0.756
ENSCPOP00000029297
annotation not available
 
 
 0.756
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.