STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INPP5DInositol polyphosphate-5-phosphatase D. (1220 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 
 0.975
SHC1
SHC adaptor protein 1.
    
 0.972
FCGR2
Low affinity immunoglobulin gamma Fc region receptor II; Binds to the Fc region of immunoglobulins gamma. Low affinity receptor.
   
 0.932
GRB2
Growth factor receptor bound protein 2.
    
0.908
Fcgr2a
Ig-like domain-containing protein.
   
 0.886
SHC3
SHC adaptor protein 3.
    
 0.884
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.855
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.850
H0W027_CAVPO
Uncharacterized protein.
    
 0.839
LOC100734206
Uncharacterized protein.
    
 0.832
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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