node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F12 | HABP2 | ENSCPOP00000018858 | ENSCPOP00000027059 | Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). | Hyaluronan binding protein 2. | 0.594 |
F12 | HGFAC | ENSCPOP00000018858 | ENSCPOP00000014346 | Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). | HGF activator. | 0.568 |
F12 | LOC100736000 | ENSCPOP00000018858 | ENSCPOP00000030670 | Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). | Uncharacterized protein. | 0.563 |
F12 | LRIT1 | ENSCPOP00000018858 | ENSCPOP00000013878 | Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). | Leucine rich repeat, Ig-like and transmembrane domains 1. | 0.819 |
F12 | LRIT3 | ENSCPOP00000018858 | ENSCPOP00000000694 | Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). | Leucine rich repeat, Ig-like and transmembrane domains 3. | 0.819 |
F12 | PTPN11 | ENSCPOP00000018858 | ENSCPOP00000012179 | Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.551 |
F12 | PTPN6 | ENSCPOP00000018858 | ENSCPOP00000027096 | Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.551 |
F12 | PTPRC | ENSCPOP00000018858 | ENSCPOP00000028696 | Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). | Protein tyrosine phosphatase receptor type C. | 0.434 |
HABP2 | F12 | ENSCPOP00000027059 | ENSCPOP00000018858 | Hyaluronan binding protein 2. | Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). | 0.594 |
HABP2 | HGFAC | ENSCPOP00000027059 | ENSCPOP00000014346 | Hyaluronan binding protein 2. | HGF activator. | 0.583 |
HABP2 | LOC100736000 | ENSCPOP00000027059 | ENSCPOP00000030670 | Hyaluronan binding protein 2. | Uncharacterized protein. | 0.563 |
HABP2 | LRIT1 | ENSCPOP00000027059 | ENSCPOP00000013878 | Hyaluronan binding protein 2. | Leucine rich repeat, Ig-like and transmembrane domains 1. | 0.819 |
HABP2 | LRIT3 | ENSCPOP00000027059 | ENSCPOP00000000694 | Hyaluronan binding protein 2. | Leucine rich repeat, Ig-like and transmembrane domains 3. | 0.819 |
HABP2 | PTPN11 | ENSCPOP00000027059 | ENSCPOP00000012179 | Hyaluronan binding protein 2. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.551 |
HABP2 | PTPN6 | ENSCPOP00000027059 | ENSCPOP00000027096 | Hyaluronan binding protein 2. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.551 |
HABP2 | PTPRC | ENSCPOP00000027059 | ENSCPOP00000028696 | Hyaluronan binding protein 2. | Protein tyrosine phosphatase receptor type C. | 0.450 |
HGFAC | F12 | ENSCPOP00000014346 | ENSCPOP00000018858 | HGF activator. | Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). | 0.568 |
HGFAC | HABP2 | ENSCPOP00000014346 | ENSCPOP00000027059 | HGF activator. | Hyaluronan binding protein 2. | 0.583 |
HGFAC | LOC100736000 | ENSCPOP00000014346 | ENSCPOP00000030670 | HGF activator. | Uncharacterized protein. | 0.563 |
HGFAC | LRIT1 | ENSCPOP00000014346 | ENSCPOP00000013878 | HGF activator. | Leucine rich repeat, Ig-like and transmembrane domains 1. | 0.819 |