STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)    
Predicted Functional Partners:
CD40
CD40 molecule.
   
 0.999
ICOS
Inducible T cell costimulator.
  
 
 0.984
Cd4
Uncharacterized protein.
   
 
 0.909
Faslg
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
   
 
 0.883
TNC
Tenascin C.
    
   0.881
LTBR
Lymphotoxin beta receptor.
    
 0.877
Tnfrsf14
HVEM.
   
 0.868
FAS
Fas cell surface death receptor.
   
 
 0.852
TNR
Tenascin R.
    
   0.847
TNN
Tenascin N.
    
   0.847
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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