STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MOGAT2Monoacylglycerol O-acyltransferase 2. (305 aa)    
Predicted Functional Partners:
DGAT1
O-acyltransferase.
    
 0.962
PNPLA2
Patatin like phospholipase domain containing 2.
     
 0.925
DGAT2
Diacylglycerol O-acyltransferase 2.
  
 
0.923
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
   
 
 0.921
PLPP4
Phospholipid phosphatase 4.
     
 0.920
PLPP5
Phospholipid phosphatase 5.
     
 0.920
PLPP2
Phospholipid phosphatase 2.
     
 0.917
DGKZ
Diacylglycerol kinase.
     
 0.913
DGKH
Diacylglycerol kinase.
     
 0.912
PNLIPRP2
Pancreatic lipase-related protein 2; Lipase with broad substrate specificity. Can hydrolyze both phospholipids and galactolipids. Acts preferentially on monoglycerides, phospholipids and galactolipids. Contributes to milk fat hydrolysis (By similarity); Belongs to the AB hydrolase superfamily. Lipase family.
     
 0.909
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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