STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTP4A3Protein tyrosine phosphatase 4A3. (173 aa)    
Predicted Functional Partners:
Cnnm3
Uncharacterized protein.
    
 
 0.920
Csnk2a1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
     
 0.770
RABGGTB
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 0.746
CNNM4
Cyclin and CBS domain divalent metal cation transport mediator 4.
    
 
 0.669
CNNM2
Cyclin and CBS domain divalent metal cation transport mediator 2.
    
 
 0.651
CNNM1
Cyclin and CBS domain divalent metal cation transport mediator 1.
    
 
 0.575
EPHX2
Epoxide hydrolase 2.
   
  
 0.562
ESR2
Estrogen receptor 2.
      
 0.532
LCK
Tyrosine-protein kinase.
    
 
 0.444
ESR1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
      
 0.438
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.