STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AZGP1Alpha-2-glycoprotein 1, zinc-binding; Belongs to the MHC class I family. (352 aa)    
Predicted Functional Partners:
PIP
Prolactin-inducible protein homolog; Belongs to the PIP family.
   
 0.959
APOH
Apolipoprotein H.
   
 0.797
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
    
 0.753
RPA2
Replication protein A2.
    
 0.722
HRG
Histidine rich glycoprotein.
   
  
 0.708
SASS6
SAS-6 centriolar assembly protein.
    
 0.704
STN1
CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
    
 0.704
H0VA20_CAVPO
Ig-like domain-containing protein.
    
 0.688
LOC101787542
Ig-like domain-containing protein.
    
 0.688
AFM
Afamin.
   
 
 0.641
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.