STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (486 aa)    
Predicted Functional Partners:
HAMP
Hepcidin antimicrobial peptide.
    
 
 0.967
HEPH
Hephaestin; Belongs to the multicopper oxidase family.
    
 0.885
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
    
 0.837
HEPHL1
Hephaestin like 1; Belongs to the multicopper oxidase family.
    
 0.783
TFR2
Transferrin receptor 2.
      
 0.764
F5
Coagulation factor V; Belongs to the multicopper oxidase family.
    
 0.735
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
    
 0.735
RS1
Retinoschisin 1.
    
 0.725
SLC11A2
Solute carrier family 11 member 2.
      
 0.712
HFE
Homeostatic iron regulator; Belongs to the MHC class I family.
      
 0.695
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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