STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNOCyclin O; Belongs to the cyclin family. (299 aa)    
Predicted Functional Partners:
CDC20
Cell division cycle 20.
   
 0.867
CDC20B
Cell division cycle 20B.
   
 0.867
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.852
INTU
Inturned planar cell polarity protein.
   
 0.845
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.817
Wee2
Wee1-like protein kinase.
   
 0.803
H0W9P9_CAVPO
Wee1-like protein kinase.
   
 0.803
CDC27
Cell division cycle 27.
    
 0.797
WEE1
Wee1-like protein kinase.
   
 0.787
PKMYT1
Protein kinase, membrane associated tyrosine/threonine 1; Belongs to the protein kinase superfamily.
   
 0.786
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.