KLHL38 protein (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KLHL38

Kelch like family member 38. (576 aa)

Predicted Functional Partners:

CUL3

0.780

CUL1

0.752

BBS9

0.686

TTC8

0.663

MIB2

0.653

BBS7

0.647

RBX1

0.638

NANP

0.638

RSPH3

0.625

MAD2L2

0.622

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS7	BBS9	ENSCPOP00000001110	ENSCPOP00000000840	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Bardet-Biedl syndrome 9.	0.998
BBS7	KLHL38	ENSCPOP00000001110	ENSCPOP00000031913	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Kelch like family member 38.	0.647
BBS7	TTC8	ENSCPOP00000001110	ENSCPOP00000000619	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Tetratricopeptide repeat domain 8.	0.994
BBS9	BBS7	ENSCPOP00000000840	ENSCPOP00000001110	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.998
BBS9	KLHL38	ENSCPOP00000000840	ENSCPOP00000031913	Bardet-Biedl syndrome 9.	Kelch like family member 38.	0.686
BBS9	TTC8	ENSCPOP00000000840	ENSCPOP00000000619	Bardet-Biedl syndrome 9.	Tetratricopeptide repeat domain 8.	0.997
CUL1	CUL3	ENSCPOP00000016460	ENSCPOP00000005101	Cullin 1; Belongs to the cullin family.	Cullin 3; Belongs to the cullin family.	0.838
CUL1	KLHL38	ENSCPOP00000016460	ENSCPOP00000031913	Cullin 1; Belongs to the cullin family.	Kelch like family member 38.	0.752
CUL1	MIB2	ENSCPOP00000016460	ENSCPOP00000020436	Cullin 1; Belongs to the cullin family.	Mindbomb E3 ubiquitin protein ligase 2.	0.876
CUL1	RBX1	ENSCPOP00000016460	ENSCPOP00000025414	Cullin 1; Belongs to the cullin family.	Ring-box 1.	0.999
CUL3	CUL1	ENSCPOP00000005101	ENSCPOP00000016460	Cullin 3; Belongs to the cullin family.	Cullin 1; Belongs to the cullin family.	0.838
CUL3	KLHL38	ENSCPOP00000005101	ENSCPOP00000031913	Cullin 3; Belongs to the cullin family.	Kelch like family member 38.	0.780
CUL3	MIB2	ENSCPOP00000005101	ENSCPOP00000020436	Cullin 3; Belongs to the cullin family.	Mindbomb E3 ubiquitin protein ligase 2.	0.876
CUL3	RBX1	ENSCPOP00000005101	ENSCPOP00000025414	Cullin 3; Belongs to the cullin family.	Ring-box 1.	0.999
KLHL38	BBS7	ENSCPOP00000031913	ENSCPOP00000001110	Kelch like family member 38.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.647
KLHL38	BBS9	ENSCPOP00000031913	ENSCPOP00000000840	Kelch like family member 38.	Bardet-Biedl syndrome 9.	0.686
KLHL38	CUL1	ENSCPOP00000031913	ENSCPOP00000016460	Kelch like family member 38.	Cullin 1; Belongs to the cullin family.	0.752
KLHL38	CUL3	ENSCPOP00000031913	ENSCPOP00000005101	Kelch like family member 38.	Cullin 3; Belongs to the cullin family.	0.780
KLHL38	MAD2L2	ENSCPOP00000031913	ENSCPOP00000017570	Kelch like family member 38.	Mitotic arrest deficient 2 like 2.	0.622
KLHL38	MIB2	ENSCPOP00000031913	ENSCPOP00000020436	Kelch like family member 38.	Mindbomb E3 ubiquitin protein ligase 2.	0.653