STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLA2G5Phospholipase A(2). (138 aa)    
Predicted Functional Partners:
PLA2G3
Phospholipase A2 group III.
     
 0.909
PLA2G12B
Phospholipase A2 group XIIB.
     
 0.889
PLA2G12A
Phospholipase A2 group XIIA.
     
 0.860
PLB1
Phospholipase B1, membrane-associated; Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity). Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily.
     
 0.842
PLAAT3
Phospholipase A and acyltransferase 3.
     
 0.835
PLA2G15
Phospholipase A2 group XV.
     
 0.832
PLA2G1B
Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family.
  
  
0.820
PLA2G4A
Phospholipase A2.
     
 0.818
PAFAH1B3
Platelet activating factor acetylhydrolase 1b catalytic subunit 3.
     
 0.816
PLA2G10
Phospholipase A(2).
  
  
0.808
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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