STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ING5Inhibitor of growth protein. (213 aa)    
Predicted Functional Partners:
MEAF6
MYST/Esa1 associated factor 6.
   
 0.961
KAT6A
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.944
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.944
KAT7
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.941
BRPF1
Bromodomain and PHD finger containing 1.
    
 0.935
BRPF3
Bromodomain and PHD finger containing 3.
    
 0.898
BRD1
Bromodomain containing 1.
    
 0.885
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]
    
 0.868
JADE2
Jade family PHD finger 2.
    
 0.838
JADE1
Jade family PHD finger 1.
    
 0.836
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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