STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHMRab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. (651 aa)    
Predicted Functional Partners:
RABGGTA
Rab geranylgeranyltransferase subunit alpha.
    
 0.993
RAB7A
RAB7A, member RAS oncogene family.
    
 0.984
Rabgef1
Uncharacterized protein.
     
 0.977
RABGGTB
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 0.972
PTAR1
Protein prenyltransferase alpha subunit repeat containing 1.
   
 0.970
RAB1A
RAB1A, member RAS oncogene family.
    
 0.865
RAB1B
RAB1B, member RAS oncogene family.
    
 0.862
RAB3A
RAB3A, member RAS oncogene family.
    
 0.836
RAB18
RAB18, member RAS oncogene family.
     
 0.824
RAB9A
RAB9A, member RAS oncogene family.
    
 0.823
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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