TFAM protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TFAM

Transcription factor A, mitochondrial. (228 aa)

Predicted Functional Partners:

ENSODEP00000018636

0.998

ENSODEP00000011314

0.989

CLPP

0.974

LONP1

0.927

ENSODEP00000003836

0.906

ENSODEP00000022613

0.906

TFB1M

0.899

ATP5F1A

0.886

SARS1

0.885

ACO2

0.885

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACO2	ATP5F1A	ENSODEP00000017031	ENSODEP00000025085	Aconitase 2.	ATP synthase F1 subunit alpha.	0.997
ACO2	CLPP	ENSODEP00000017031	ENSODEP00000021011	Aconitase 2.	Caseinolytic mitochondrial matrix peptidase proteolytic subunit.	0.971
ACO2	ENSODEP00000003836	ENSODEP00000017031	ENSODEP00000003836	Aconitase 2.	annotation not available	0.848
ACO2	ENSODEP00000011314	ENSODEP00000017031	ENSODEP00000011314	Aconitase 2.	annotation not available	0.457
ACO2	ENSODEP00000022613	ENSODEP00000017031	ENSODEP00000022613	Aconitase 2.	annotation not available	0.848
ACO2	LONP1	ENSODEP00000017031	ENSODEP00000020429	Aconitase 2.	Lon peptidase 1, mitochondrial.	0.951
ACO2	TFAM	ENSODEP00000017031	ENSODEP00000001027	Aconitase 2.	Transcription factor A, mitochondrial.	0.885
ATP5F1A	ACO2	ENSODEP00000025085	ENSODEP00000017031	ATP synthase F1 subunit alpha.	Aconitase 2.	0.997
ATP5F1A	CLPP	ENSODEP00000025085	ENSODEP00000021011	ATP synthase F1 subunit alpha.	Caseinolytic mitochondrial matrix peptidase proteolytic subunit.	0.918
ATP5F1A	ENSODEP00000003836	ENSODEP00000025085	ENSODEP00000003836	ATP synthase F1 subunit alpha.	annotation not available	0.921
ATP5F1A	ENSODEP00000011314	ENSODEP00000025085	ENSODEP00000011314	ATP synthase F1 subunit alpha.	annotation not available	0.427
ATP5F1A	ENSODEP00000022613	ENSODEP00000025085	ENSODEP00000022613	ATP synthase F1 subunit alpha.	annotation not available	0.921
ATP5F1A	LONP1	ENSODEP00000025085	ENSODEP00000020429	ATP synthase F1 subunit alpha.	Lon peptidase 1, mitochondrial.	0.865
ATP5F1A	TFAM	ENSODEP00000025085	ENSODEP00000001027	ATP synthase F1 subunit alpha.	Transcription factor A, mitochondrial.	0.886
CLPP	ACO2	ENSODEP00000021011	ENSODEP00000017031	Caseinolytic mitochondrial matrix peptidase proteolytic subunit.	Aconitase 2.	0.971
CLPP	ATP5F1A	ENSODEP00000021011	ENSODEP00000025085	Caseinolytic mitochondrial matrix peptidase proteolytic subunit.	ATP synthase F1 subunit alpha.	0.918
CLPP	LONP1	ENSODEP00000021011	ENSODEP00000020429	Caseinolytic mitochondrial matrix peptidase proteolytic subunit.	Lon peptidase 1, mitochondrial.	0.891
CLPP	TFAM	ENSODEP00000021011	ENSODEP00000001027	Caseinolytic mitochondrial matrix peptidase proteolytic subunit.	Transcription factor A, mitochondrial.	0.974
ENSODEP00000003836	ACO2	ENSODEP00000003836	ENSODEP00000017031	annotation not available	Aconitase 2.	0.848
ENSODEP00000003836	ATP5F1A	ENSODEP00000003836	ENSODEP00000025085	annotation not available	ATP synthase F1 subunit alpha.	0.921