Hdac2 protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Gene Fusion

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[Homology]

Score

Hdac2

annotation not available (488 aa)

Predicted Functional Partners:

Chd4

0.995

ENSODEP00000004979

0.995

ENSODEP00000026545

0.995

SAP30

0.993

RCOR1

0.992

SIN3A

0.992

ENSODEP00000004935

0.990

ENSODEP00000006880

0.990

CHD3

0.989

MTA1

0.986

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD3	Chd4	ENSODEP00000024307	ENSODEP00000004080	Chromodomain helicase DNA binding protein 3.	Chromodomain helicase DNA binding protein 4.	0.999
CHD3	ENSODEP00000004935	ENSODEP00000024307	ENSODEP00000004935	Chromodomain helicase DNA binding protein 3.	annotation not available	0.975
CHD3	ENSODEP00000004979	ENSODEP00000024307	ENSODEP00000004979	Chromodomain helicase DNA binding protein 3.	annotation not available	0.988
CHD3	ENSODEP00000006880	ENSODEP00000024307	ENSODEP00000006880	Chromodomain helicase DNA binding protein 3.	annotation not available	0.975
CHD3	ENSODEP00000026545	ENSODEP00000024307	ENSODEP00000026545	Chromodomain helicase DNA binding protein 3.	annotation not available	0.988
CHD3	Hdac2	ENSODEP00000024307	ENSODEP00000001037	Chromodomain helicase DNA binding protein 3.	annotation not available	0.989
CHD3	MTA1	ENSODEP00000024307	ENSODEP00000003375	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1.	0.995
CHD3	RCOR1	ENSODEP00000024307	ENSODEP00000003245	Chromodomain helicase DNA binding protein 3.	REST corepressor 1.	0.883
CHD3	SAP30	ENSODEP00000024307	ENSODEP00000015726	Chromodomain helicase DNA binding protein 3.	Sin3A associated protein 30.	0.858
CHD3	SIN3A	ENSODEP00000024307	ENSODEP00000020215	Chromodomain helicase DNA binding protein 3.	SIN3 transcription regulator family member A.	0.873
Chd4	CHD3	ENSODEP00000004080	ENSODEP00000024307	Chromodomain helicase DNA binding protein 4.	Chromodomain helicase DNA binding protein 3.	0.999
Chd4	ENSODEP00000004935	ENSODEP00000004080	ENSODEP00000004935	Chromodomain helicase DNA binding protein 4.	annotation not available	0.990
Chd4	ENSODEP00000004979	ENSODEP00000004080	ENSODEP00000004979	Chromodomain helicase DNA binding protein 4.	annotation not available	0.995
Chd4	ENSODEP00000006880	ENSODEP00000004080	ENSODEP00000006880	Chromodomain helicase DNA binding protein 4.	annotation not available	0.990
Chd4	ENSODEP00000026545	ENSODEP00000004080	ENSODEP00000026545	Chromodomain helicase DNA binding protein 4.	annotation not available	0.995
Chd4	Hdac2	ENSODEP00000004080	ENSODEP00000001037	Chromodomain helicase DNA binding protein 4.	annotation not available	0.995
Chd4	MTA1	ENSODEP00000004080	ENSODEP00000003375	Chromodomain helicase DNA binding protein 4.	Metastasis associated 1.	0.996
Chd4	RCOR1	ENSODEP00000004080	ENSODEP00000003245	Chromodomain helicase DNA binding protein 4.	REST corepressor 1.	0.891
Chd4	SAP30	ENSODEP00000004080	ENSODEP00000015726	Chromodomain helicase DNA binding protein 4.	Sin3A associated protein 30.	0.894
Chd4	SIN3A	ENSODEP00000004080	ENSODEP00000020215	Chromodomain helicase DNA binding protein 4.	SIN3 transcription regulator family member A.	0.909