MSH4 protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MSH4

mutS homolog 4. (930 aa)

Predicted Functional Partners:

ENSODEP00000024109

0.997

ENSODEP00000020935

0.993

MLH1

0.978

Pms1

0.964

ENSODEP00000016418

0.959

RAD51

0.955

BLM

0.946

ENSODEP00000007011

0.914

ENSODEP00000017844

0.911

RECQL4

0.910

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLM	ENSODEP00000007011	ENSODEP00000020850	ENSODEP00000007011	BLM RecQ like helicase.	annotation not available	0.999
BLM	ENSODEP00000016418	ENSODEP00000020850	ENSODEP00000016418	BLM RecQ like helicase.	annotation not available	0.810
BLM	ENSODEP00000017844	ENSODEP00000020850	ENSODEP00000017844	BLM RecQ like helicase.	annotation not available	0.997
BLM	ENSODEP00000020935	ENSODEP00000020850	ENSODEP00000020935	BLM RecQ like helicase.	annotation not available	0.942
BLM	ENSODEP00000024109	ENSODEP00000020850	ENSODEP00000024109	BLM RecQ like helicase.	annotation not available	0.946
BLM	MLH1	ENSODEP00000020850	ENSODEP00000008181	BLM RecQ like helicase.	mutL homolog 1.	0.989
BLM	MSH4	ENSODEP00000020850	ENSODEP00000001039	BLM RecQ like helicase.	mutS homolog 4.	0.946
BLM	Pms1	ENSODEP00000020850	ENSODEP00000014589	BLM RecQ like helicase.	annotation not available	0.784
BLM	RAD51	ENSODEP00000020850	ENSODEP00000023373	BLM RecQ like helicase.	RAD51 recombinase.	0.996
ENSODEP00000007011	BLM	ENSODEP00000007011	ENSODEP00000020850	annotation not available	BLM RecQ like helicase.	0.999
ENSODEP00000007011	ENSODEP00000016418	ENSODEP00000007011	ENSODEP00000016418	annotation not available	annotation not available	0.588
ENSODEP00000007011	ENSODEP00000017844	ENSODEP00000007011	ENSODEP00000017844	annotation not available	annotation not available	0.927
ENSODEP00000007011	ENSODEP00000020935	ENSODEP00000007011	ENSODEP00000020935	annotation not available	annotation not available	0.848
ENSODEP00000007011	ENSODEP00000024109	ENSODEP00000007011	ENSODEP00000024109	annotation not available	annotation not available	0.912
ENSODEP00000007011	MLH1	ENSODEP00000007011	ENSODEP00000008181	annotation not available	mutL homolog 1.	0.953
ENSODEP00000007011	MSH4	ENSODEP00000007011	ENSODEP00000001039	annotation not available	mutS homolog 4.	0.914
ENSODEP00000007011	Pms1	ENSODEP00000007011	ENSODEP00000014589	annotation not available	annotation not available	0.585
ENSODEP00000007011	RAD51	ENSODEP00000007011	ENSODEP00000023373	annotation not available	RAD51 recombinase.	0.990
ENSODEP00000007011	RECQL4	ENSODEP00000007011	ENSODEP00000016415	annotation not available	RecQ like helicase 4.	0.986
ENSODEP00000016418	BLM	ENSODEP00000016418	ENSODEP00000020850	annotation not available	BLM RecQ like helicase.	0.810