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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSODEP00000001237annotation not available (425 aa)    
Predicted Functional Partners:
PLK4
Polo like kinase 4.
    
 0.997
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.982
SASS6
SAS-6 centriolar assembly protein.
    
 0.963
NYNRIN
NYN domain and retroviral integrase containing.
    
 0.958
RUVBL1
RuvB like AAA ATPase 1.
    
 0.955
STIL
STIL centriolar assembly protein.
   
 0.953
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
    
 0.951
CEP152
Centrosomal protein 152.
    
 0.949
ENSODEP00000015307
annotation not available
    
 0.949
TRRAP
Transformation/transcription domain associated protein.
   
 0.948
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.